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Males with ALS die faster, on average, than females.

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Connor said the variant may not have had time to accelerate the pace of the disease in male mice. The crossbred mice performed ificantly worse on tests of forelimb and relatiohship grip strength and had a 4 percent shorter life-span.

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The crossbred mice showed increased oxidative stress and microglial activation. The mice were also found relatkonship have disruption of the neurofilaments, the tiny cables that transport nutrients through nerve cells.

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